Thevetia peruviana is an always green tree that grows well at adverse conditions and it is well adapted to Yucatan weather. Its kernal contains more than 60% of oil. Because the toxicity of the plat the oil is non edible and then a good candidate for biofuel production. In this study it is reported the results of supercritical extraction of oil from Thevetia peruviana kernals. The yield obtained 70% is higher than that obtained using solvent extraction 62% with petroleum ether, 60% with n-hexane, and to 40% using mechanical extraction.