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HPR-Series High Pressure Chemical Reactors

  • Stirred Reactor Vessel from 50 ml to 4 Liter Capacity
  • Operate up to 10,000 psi (689 Bar / 68.9 MPa) and 350°C
  • Magnetic Drive Mixing
  • Safety Rupture Disc Assembly
  • Integrated Controller with Color Touch Screen
  • Data Export via a Flash Drive Communications Port
  • Optional Reagent Addition Modules
  • Optional Vessel Windows (Up to 150°C Operation)

The HPR-Series of pressure chemical reactors is designed for researchers who are interested in investigating the feasibility of pressurized chemical reactions or processing problems in their laboratories. Whether it is repetitive pressurized laboratory chemical synthesis, teaching laboratory applications, or process development, the HPR-Series is an excellent unit for your application needs.

The HPR reactors range in size from 50 ml to 8 liters and may be operated up to 10,000 psi and 350°C. Two standard pressure vessel types are available. Bolted closures may be operated up to 2350 psi and 350°C. Hand-tight closures may be operated up to 10,000 psi and 200°C. Other custom vessels for specialized applications are available.

The reactors are equipped with magnetically coupled impellers for optimal mixing. All high pressure components are ASME compliant design (code stamp available) and protected by a rupture disc for safe operations. These laboratory bench top models are ideal for applications where repetitive use makes convenience a necessity. A few examples include: catalytic studies, polymerization, hydrogenation, oxidation, isomerization, and dehydrogenation. All size reactors are supplied as ready-to-use instruments requiring only utility connections prior to operation. The reactors are compact instruments that fit easily into a fume hood. Their modular design makes it easy and cost effective to alter the unit’s basic configuration, adapting it to meet new or evolving application needs.

All functions are controlled by an integrated processor with a full color touch screen: Closed loop temperature control, closed loop speed control, pressure indication, over-temperature limit control, ramp/soak programming of temperature and mixer speed. An RS-232 communications port provides the ability to export data to an external computer.

Options for the HPR Series Reactors include: vessel windows, sapphire windows, additional ports, cooling coils, sample loops, baffles, and reagent addition modules.

Areas of Investigation

  • Alkylation
  • Amination
  • Biotechnology
  • Carboxylation
  • Catalytic reduction
  • Fermentation
  • Halogenation
  • Hydrolysis
  • Isomerization
  • Nitration
  • Oxidation
  • Polymerization
  • Hydrogenation and dehydrogenation
  • Toxic/hazardous substance processing

Reactor Vessel Assembly

Pressure Vessel Sizes: 50, 100, 300, 500, 1000, 2000, 4000, and 8000 ml
Pressure Rating: Up to 10,000 psi (689 Bar and 68.9 MPa) @ 350°C
Pressure Vessel Material: 316 or 17-4-PH stainless steel on all wetted parts

Internal Dimensions (Bolted Closure):

(Operation up to 2,350 psi @ 350°C)

50 ml: 2.0 inch ID x 3.45 inch IL
100 ml: 1.5 inch ID x 3.80 inch IL
300 ml: 2.63 inch ID x 3.50 inch IL
500 ml: 2.63 inch ID x 5.80 inch IL
1000 ml: 3.63 inch ID x 6.29 inch IL
2000 ml: 3.63 inch ID x 11.95 inch IL
4000 ml: 5.31 inch ID x 11.75 inch IL
8000 ml: 6.50 inch ID x 14.0 inch IL

Internal Dimensions (Hand-Tight Closures):

(Operation up to 10,000 psi @ 200°C)

300 ml: 2.12 inch ID x 6.0 inch IL
500 ml: 2.12 inch ID x 9.0 inch IL
1000 ml: 3.0 inch ID x 8.8 inch IL
2000 ml: 4.0 inch ID x 9.8 inch IL
4000 ml: 5.5 inch ID x 10.5 inch IL
8000 ml: 5.5 inch ID x 21.0 inch IL

Main Seal: Self-energizing metal seal or various o-ring materials for lower temperature operation

Standard Features

Support Structure: Corrosion resistant bench stand
Power Requirements(US): 220 VAC/60Hz (International power rating available).
Heater: Stainless steel sheathed ceramic heater, 115-230 VAC, 50-60 Hz.
Process valves: 1/8″ OD Compression Fitting, 2 way straight valves (1/4″ OD Compression Fitting, 2 way straight valves)
Safety Head: Union style with rupture disc Thermowell: 1/8″ OD Compression Fitting


Agitator: Top head, center
Rupture disc connection: 1/4″ Cone Threaded Fitting
(2) Process connection: 1/8″ OD Compression Fitting
Sampling tube: 1/8″ OD Compression Fitting
Cooling coil: in and out 1/8″ OD Compression Fitting

Controller Specification

The unit utilizes a microcontroller to perform all PID, ramp/soak, and interlock functions. The microcontroller and power control components are located in a module which may reside on a benchtop. The digital displays and pushbuttons are located on the operator panel on the face of the cabinet.

  • Closed Loop Temperature Control
  • Closed Loop Agitator Speed Control
  • Pressure Indication (including transducer)
  • Overtemperature Limit Control
  • Ramp Soak Programming of Temperature and Speed (5 ramp/soak segments)
  • Temperature, Speed and Pressure On-Screen Plotting
  • PID Autotuning
  • Temperature, Pressure and Speed Alarms with Alarm History Storage
  • RS-232 Communications Port

Agitator Drive Assembly

Mixers: Dyna/Mag model MM-006 magnetic drive mixer, 6 in-lbs. torque, 1/4 HP Dyna/Mag model MM-016 magnetic drive mixer, 16 in-lbs. torque, 1/2 HP
Drive: DC variable speed drive, 115/1/60 Impeller: Gaspersator standard, options available
Operating Speed: 0-2500 RPM, subject to process conditions
Operating Pressure Options: 2,350 psi, 6,000 psi, and 10,000 psi

Optional Accessories (may not be available in all vessels)

  • Cooling coil: 1/8″ OD tube, U shaped
  • Sample tube: 1/8″ OD tube
  • Additional ports
  • Windows, Sapphire Windows also available
  • Internal baffles